SMALLPOX VACCINE, Dried, Calf Lymph Type
Summary of Package Insert

Dryvax, Wyeth Laboratories, Marietta, PA (1960)

Ingredients
brilliant green:
calf lymph
chloriatracycline hydrochloride;
dihydrostreptomycin sulfate;
glycerin;
neomycin sulfate;
phenol;
polymixin B sulfate.

Facts
Complications rates per million primary U.S. smallpox vaccinations

"smallpox vaccine should never be used therapeutically:"

complications occurred, especially in patients with underlying diseases or recipients of therapy impaired immune systems or in persons who had not been vaccinated for many years;

In May 1990, at the World Health Assembly, the World Health Organization declared a smallpox free world;

2-pronged vaccine needle used.

Warnings
intervals of about 2 days to 2 weeks between live virus vaccines should always be avoided:

in past, recommendations of intervals of one month between live virus vaccines;

simultaneous live virus vaccines offer advantages: threat of existing exposure, individual inaccessible for further vaccinations; or when 1-month interval would disrupt vaccination programs; these are valid reasons for simultaneous administration of poliovirus, measles, smallpox and yellow fever vaccines, provided no contraindication for the individual vaccines; if the theoretically desirable 1-month interval not feasible, vaccines should be given on the same day at different sites;

Dryvax not used after expiration date regardless of dry or reconstituted form;

In the 2-part process, if needle touches skin after dropping vaccine on injection site, do not re-dip needle into vaccine;
before disposal, vaccine vial, stopper, needle burned, boiled or autoclaved

Contraindications
infants failing to thrive;
individuals with eczema, other skin conditions, wounds, burns; siblings or household contacts of these individuals;

persons receiving x-ray, ACTH, steroids, immunosuppressive drugs;
people with gamma globulin synthesis disorders;
people with leukemia, lymphomas, malignancies affecting bone marrow or lymphatic systems;
pregnant women
prevention or treatment of recurrent herpes, warts, or any other diseases.

Precautions
only 2 or 3 needle punctures recommended for primary vaccination; 15 for revaccination;
site inspection 6-8 days post vaccination for a crusty or ulcerous legion; if note observed, repeat vaccination with another vaccine lot until successful result.

Adverse Reactions
Body: vomiting; in weak or aged persons;
Hypersensitivity: secondary pus at site infections;
Nervous system: brain disease, brain and spinal cord inflammation with fever, headache, neck and back pain; seizures, comas, peripheral nerve inflammation; permanent nervous system abnormalities;

Skin: itchy rash with blisters and crusts, hives, redness, widespread rashes;

Special Senses: accidents, eye infection may result in blindness;

Other: death, widespread smallpox/cowpox; severe disability, smallpox/cowpox cell death; accidental infection.

For compete information, ask your doctor for Smallpox Vaccine package insert.

ILLINOIS VACCINE AWARENESS COALITION (IVAC)
P.O. Box 946, Oak Park, IL 60303