Immunization Advisory Committee Meeting
March 8, 2001
10:30 am to 12:30 pm
James R. Thompson Center
9th Floor, Conference Room 032
Chicago, Illinois

Meeting Agenda

I. Call to Order
II. Approval of minutes
III. Old Business
A. Review of Proposed Changes to the Immunization Rules
B. Update on Proposed Varicella Vaccine Requirement by the State Board of Health
IV. New Business
A. Tracking Our Toddlers Shots (TOTS) Update
V. Future Meeting Dates and Agenda Items
VI. Adjournment

Institute of Medicine's (IOM) Immunization Safety Review
The second meeting of the Institute of Medicine's Immunization Safety Review Committee will be held on March 8-10, 2001 in the National Academy of Sciences Building on 2101 Constitution Ave., NW Washington, DC. March 8th will be open to the public.

March 9-10th will be closed sessions. The topic of this meeting will be on MMR vaccine and autism. An agenda is posted below and is also on their website at www.iom.edu/imsafety.

IOM will have an audio version of the entire meeting on their website by March 20. They will also make available a copy of the slide presentations within a couple of days after the meeting.

Institute of Medicine
Immunization Safety Review Committee
National Academy of Sciences
2101 Constitution Ave., NW, Washington, DC
March 8, 2001

DRAFT AGENDA

Thursday, March 8, 2001 (Lecture Room, NAS Building)
SESSION I: ETIOLOGY, DIAGNOSIS, AND EPIDEMIOLOGY OF AUTISM

8:30 - 8:35am Opening Remarks
Marie McCormick, MD, ScD
Chair, Immunization Safety Review Committee

8:35 - 9:00 Neurobiology and neuropathology of autism
Margaret Bauman, MD
Department of Neurology
Harvard Medical School

9:00 - 9:30 Etiology of autism and NIH research
Marie Bristol-Power, PhD
Special Assistant on Autism
Office of the Director, NICHD
National Institutes of Health

9:30 - 10:00 Diagnosis and assessment of autism
Fred Volkmar, MD
Professor of Child Psychiatry, Pediatrics, and Psychology
Yale Child Study Center

10:00 - 10:15 Break

10:15 - 10:45 Epidemiological evidence on rates of autism and time trends
Eric Fombonne, MD, FRCPsych
Reader in Epidemiological Child Psychiatry,
Institute of Psychiatry
King's College London

10:45 - 11:00 Trends in students with autism in IDEA programs
Louis Danielson, PhD
Director of Research to Practice Division
Office of Special Education Programs
Department of Education

11:00 - 11:45 Discussion

Discussion Panel:
Kathryn Carbone, MD
Chief, Laboratory of Pediatric and Respiratory Viral Diseases
DVP/OVRR/CBER/FDA

Ezra Susser, MD
Division of Epidemiology
Columbia University

Karin Nelson, MD
Senior Investigator, Neuroepidemiology Branch, NINDS
National Institutes of Health

11:45 - 12:30 Lunch

SESSION II: MMR/ IBD/ AUTISM HYPOTHESIS

12:30-1:30pm Hypothesis and data linking MMR/IBD/autism
Andrew Wakefield, MD
Royal Free & University College Medical School, United Kingdom

Scott Montgomery, PhD
Karolinska Institute, Sweden

1:30 - 2:00 Overview of epidemiological studies examining MMR, IBD, and
autism
Michael Stoto, PhD
Chair, Department of Epidemiology
George Washington University

2:00 - 2:30 New data and research findings regarding the link between MMR, bowel symptoms, and autism
Eric Fombonne, MD, FRCPsych
Reader in Epidemiological Child Psychiatry
Institute of Psychiatry
King's College London

2:30 - 2:45 Break

2:45 - 3:45 Discussion

Discussion Panel:
Brian Ward, MD
Associate Professor (Medicine & Microbiology), McGill University and
Montreal General Hospital Research Institute

Kathryn Carbone, MD
Chief, Laboratory of Pediatric and Respiratory Viral Diseases
DVP/OVRR/CBER/FDA

Fred Volkmar, MD
Professor of Child Psychiatry, Pediatrics, and Psychology
Yale Child Study Center

Karin Nelson, MD
Senior Investigator, Neuroepidemiology Branch, NINDS
National Institutes of Health

3:45 - 4:00 Study of autism and the Vaccine Adverse Event Reporting System (VAERS)
Jane Woo, MD, MPH
Fellow, Vaccine Safety Branch
Division of Epidemiology
OBE/CBER/FDA

4:00 - 4:30 Public Comment Session

4:30 Adjourn